When things just don’t feel right, you may experience a hollow feeling in the pit of your stomach, or you might actually manifest physical symptoms such as gastric distress, perspiration, or muscle tremors. In humans and in horses, stress can create a multitude of psychological reactions ranging from mild anxiety to debilitating near panic and severe depression, and reduced immune response which can invite illness. Long term stress can produce ulcers, musculoskeletal disorders, heart irregularities, and create a host of psychological vices.